UPDATE 7pm: The highway was closed for several hours, but has since reopened.
UPDATE 3pm: Police and emergency crews remain at the scene of the crash, and the highway remains closed.
The driver of the car has been pronounced deceased at the scene.
Emergency crews are still working to extract the vehicle from under the semi-trailer.
BREAKING 1pm: The Bruce Highway at Ambrose (between Mt Larcom and Marmor) is currently closed in both directions following a very serious two vehicle crash.
The crash, between a semi trailer and car, occurred shortly before midday.
The male driver of the truck is not believed to have been injured, but the driver of the car was injured.
Neither vehicle was carrying any passengers.
The Forensic Crash Unit will be investigating and the highway is expected to remain closed for several hours.
An alterative route for passenger vehicles travelling in both directions is via Yapala Road, Ambrose.
This road is NOT suitable for heavy vehicles / trucks.
No further information is available at this stage.