AMBULANCE officers fought hard to try to save a 59-year-old woman's life, but she died while being rushed to hospital.
Police are investigating whether a medical condition may have been a factor behind the cause of the head-on collision near the Edmund Casey Bridge.
Emergency services were called to the scene of the crash in West Mackay about 8am.
A Queensland Ambulance Service spokesman said the woman had severe chest injuries and paramedics performed CPR on her while she was being taken to Mackay Base Hospital.
"Another person was transported to the hospital in a stable condition with a leg injury," he said.
A Mackay Base Hospital spokeswoman said that person was discharged from the hospital later in the day.
Meanwhile, a Lagoon St resident, who says he has been lobbying for road safety changes in that area, said the fatal crash highlighted a need for improvement to what he claims is a dangerous stretch of road.
"I am so sad it has come to this, but I knew this would happen," he said.
Although the man was aware police were investigating whether or not a medical condition may be a factor in the crash, he said there were near misses in the area all the time.
"They should be doing 50kmh over that road," he said.
"They just fly along there."
There have been 21 deaths on Mackay region roads this year.
POLICE Media have confirmed that one person has died following the crash on Mackay Bypass Rd.
Investigations are continuing as to whether that person had a pre-existing medical condition that contributed to the crash.
More to come.
TRAFFIC is currently backed up along Cemetery Rd.
Please find alternate route.
ONE person is in a very serious condition after two vehicles collided head-on on the Mackay Bypass Rd at 8am.
A Police Media spokesman said the the Edmund Casey Bridge is currently closed and police are advising people to avoid the area.
QAS, police and QFRS are currently at the scene.
More to come.