TEENAGER Andrey Rublev is preparing for his first grand slam quarter-final. His opponent, meanwhile, is getting ready for his seventh at Flushing Meadows alone.
Russian 19-year-old Rublev stunned Belgian ninth seed David Goffin 7-5, 7-6 (7/5), 6-3 to become the youngest men's player to reach the last eight since Andy Roddick in 2001.
There he will meet the world No.1 Rafael Nadal who claimed his 50th win at the US Open in dispatching Ukraine's Alexander Dolgopolov 6-2, 6-4, 6-1.
The winner is expected to take on Roger Federer in the semi-finals. Federer is, bidding for a sixth US Open and 20th major, and is playing Philipp Kohlschreiber in their round of 16 clash.
Rublev broke into the top 100 for the first time in June and is now No.53, having won 13 of his last 17 matches.
He says all the pressure will be on Nadal, who is chasing a 16th major.
"Rafa is a real champion. I will try to do my best -- I have nothing to lose," Rublev said.
Nadal, also aiming for his third US title after wins in 2010 and 2013, looked at his best after dropping the opening set of his first two matches.
"I played a solid match with not many mistakes," Nadal said.
"He (Dolgopolov) is a player who can play amazing shots but sometimes he can be very unpredictable so I just waited for my opportunity."
Women's top seed Kristina Pliskova, meanwhile, needed just 46 minutes to crush American Jennifer Brady, 6-1, 6-0 and make her third major quarter-final of 2017.
A beaten finalist in 2016, Pliskova will next face American 20th seed CoCo Vandeweghe, who made the last eight for the first time by beating Lucie Safarova of the Czech Republic 6-4, 7-6 (7/2).